Relationship between circulating E-selectin, DD genotype of angiotensin-converting-enzyme, and cardiovascular damage in central obese subjects.

نویسندگان

  • Giuseppe Licata
  • Tiziana Di Chiara
  • Anna Licata
  • Giovanni Triolo
  • Christiano Argano
  • Antonio Pinto
  • Gaspare Parrinello
  • Salvatore Corrao
  • Giovanni Duro
  • Rosario Scaglione
چکیده

Fifty-six young central obese patients were investigated to evaluate relationships between soluble E-selectin (sE-S), angiotensin-converting enzyme (ACE) gene polymorphism, left ventricular function and structure, and carotid morphology by determination of sE-S and ACE genotypes. Our results indicated that central obese subjects with concomitant higher levels of sE-S and ACE DD genotype may be characterized by early cardiovascular alterations and then considered a particular subset of subjects at higher risk of cardiovascular disease.

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عنوان ژورنال:
  • Metabolism: clinical and experimental

دوره 52 8  شماره 

صفحات  -

تاریخ انتشار 2003